Eylea (aflibercept)眼內注射治療
(Intravitreal Injection IVI)
-----視網膜靜脈阻塞所引起的黃斑部水腫
一位60多歲的女性，因為視力模糊到診所求診，之前至別家診所求診，起初以為只是白內障的問題，於是想來蕭醫師診所開白內障手術，後來經蕭醫師建議做進一步視網膜檢查時發現，除了白內障以外，尚有視網膜靜脈血管阻塞合併黃斑部水腫的問題，所以視力不良不單單只是白內障所造成。
經過三個月的點消水腫藥物治療 (Nevanac)，視力及視網膜黃斑部水腫狀況皆無改善，於是在第三個月左右決定為患者注射Eylea (aflibercept)。
Eylea (aflibercept)是一種新型藥物，有2種接受器 (anti-VEGF ＆ anti-PIGF)
注射前 2015/01/24 OS
左眼視網膜靜脈血管阻塞合併黃斑部水腫
視力嚴重下降至0.05
左眼最佳矯正視力0.05
黃斑部水腫高度519um
注射Eylea一週後 2015/06/05 OS
左眼最佳矯正視力0.4
黃斑部水腫高度215um
視力及黃斑部水腫狀況明顯改善許多
注射Eylea一個月後 2015/06/26 OS
左眼最佳矯正視力維持在0.4
黃斑部水腫高度207um
相信在白內障手術後，視力一定會更加進步。
使用Eylea (aflibercept)注射後注意事項：
在手術中可能產生之併發症並不常見，但下列情況可於手術時或手術後發生：
眼壓增高(青光眼)、或眼壓過低、白內障、飛蚊症、眼球內出血、眼球內發炎、感染或化膿、視網膜裂孔或剝離、未能治癒原視中心點病變，有部分病人手術後黃斑部水腫會持續，及需要多次注射或其他治療……等。
Information for Patients With Macular Edema Following CRVO
If you or a loved one has been diagnosed with Macular Edema following Central Retinal Vein Occlusion (CRVO) or Branch Retinal Vein Occlusion (BRVO) , you are not alone.
Each year, there are approximately 2,000 new cases of Central Retinal Vein Occlusion (CRVO) or Branch Retinal Vein Occlusion (BRVO) in Taiwan.
IMPORTANT PRESCRIBING INFORMATION FOR EYLEA® (aflibercept) INJECTION
EYLEA® (aflibercept) Injection is a prescription medicine approved for the treatment of patients with Macular Edema following CRVO or BRVO. The recommended dose for EYLEA is 2 mg administered by injection in the eye monthly (every 4 weeks).
IMPORTANT SAFETY INFORMATION FOR EYLEA® (aflibercept) INJECTION
The most common side effects reported in patients receiving EYLEA are increased redness in the eye, eye pain, cataract, moving spots in the field of vision, increased pressure in the eye, and vitreous (gel-like substance) detachment.
Serious side effects related to the injection procedure are rare but can occur including infection inside the eye, retinal detachment, cataract, increased pressure in the eye, and vitreous detachment.
參考資料：
Eylea官網 http://www.eylea.us/
